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Young Hun Lee on Muck Rack

Young Hun Lee

As seen in: The Journal of Biological Chemistry
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Articles

Syndecan-2 cytoplasmic domain upregulates Matrix Metalloproteinase-7 expression via Protein KinaseCγ mediated FAK/ERK signaling pathway in colon cancer

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By Hyejung Jung, Bohee Jang, Sojoong Choi, Young Hun Lee
| The Journal of Biological Chemistry Verified
The syndecan family of heparan sulfate proteoglycans contribute to cell adhesion and communication by serving as co-receptors for cell signaling and extracellular matrix molecules. Syndecan-2 is located at the cell surface, and we previously reported that it induces matrix metalloproteinase-7 (MMP-7) expression in colon cancer cells. However, the underlying regulatory mechanisms are unknown.
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