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Articles

Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants

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By Munjung Kim, Man Lu, Xuhui Ma, Paula Berman, Olga Khersonsky, Uwe Heinig, Liron Sulimani, Shahar Cohen, Yoav Peleg, Sagit Meir, Ilana Rogachev, David Meiri, Sarel J. Fleishman, Asaph Aharoni, Janka Höfer, Herschel Mehlman, Efrat Almekias-Siegl, Younghui Dong
| Science Magazine Verified
Abstract Psychedelic indolethylamines with therapeutic potential are naturally produced in plants, fungi, and animals. Here, we elucidated the complete N,N-dimethyltryptamine (DMT) biosynthetic pathway in hallucinogenic plant species traditionally used in shamanic rituals for spiritual healing.
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