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Yuan-Kun Liu on Muck Rack

Yuan-Kun Liu

As seen in: The BMJ
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Articles

Integrin CD11b/CD18 reprograms macrophage polarization by suppressing ERK/STAT3 signaling to enhance antitumor immunity in colitis-associated colorectal cancer

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By Ying Lin, Peng Mi, Yuan-Kun Liu
| The BMJ Verified
Colorectal cancer (CRC) remains a significant global health challenge. Chronic inflammation drives colorectal tumorigenesis by remodeling the tumor microenvironment. Although the leukocyte adhesion receptor CD11b/CD18 plays a key role in inflammation and immunity, its precise functions and mechanisms in CRC and colitis-associated colorectal cancer (CAC) are not fully elucidated.
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