Yuanhua Qiu on Muck Rack

Yuanhua Qiu

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Articles

Macrophage ferroptosis potentiates GCN2 deficiency induced pulmonary venous arterialization - Nature Communications

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By Jingyuan Zhang, Pei Mao, Tengfei Zhou, Bingqing Yue, Yaning Li, Kejing Ying, Fudi Wang, Yuanhua Qiu
| Nature
Abstract Pulmonary veno-occlusive disease (PVOD) is a fatal disease characterized by the remodelling of pulmonary veins and haemosiderin accumulation in macrophages. Although (General Control Nonderepressible 2) GCN2 deficiency has been reported in PVOD patients, the underlying mechanism by which GCN2 deficiency affects the pulmonary venous cells and the surrounding cells, remains unclear.
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