Kejing Ying
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First-Line Serplulimab in Extensive-Stage Small Cell Lung Cancer : Secondary Analysis of the ASTRUM-005 Phase 3 Randomized Clinical Trial
First-Line Serplulimab in Extensive-Stage Small Cell Lung Cancer: Secondary Analysis of the ASTRUM-005 Phase 3 Randomized Clinical Trial Key Points Question What are the long-term efficacy and safety outcomes of adding serplulimab to first-line chemotherapy for previously untreated extensive-stage small cell lung cancer (ES-SCLC)?
Macrophage ferroptosis potentiates GCN2 deficiency induced pulmonary venous arterialization - Nature Communications
Abstract Pulmonary veno-occlusive disease (PVOD) is a fatal disease characterized by the remodelling of pulmonary veins and haemosiderin accumulation in macrophages. Although (General Control Nonderepressible 2) GCN2 deficiency has been reported in PVOD patients, the underlying mechanism by which GCN2 deficiency affects the pulmonary venous cells and the surrounding cells, remains unclear.
Anti‐Helicobacter pylori Infection Treatment and Pulmonary Hypersensitivity: Case Series and Review of the Literature
CRP C-reactive protein CT computed tomography HP Helicobacter pylori PPI proton pump inhibitor WBC white blood cell count 1 Introduction Helicobacter pylori (H. pylori) is a gram-negative spiral-shaped bacterium that commonly colonizes the gastric mucosa of over half of the world's population [1]. H. pylori infection is typically acquired in childhood through oral-oral or fecal-oral transmission [2, 3] and can lead to various diseases such as gastritis, peptic ulcer, and gastric cancer [4, 5].
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