Abstract Introduction Tau hyperphosphorylation, mitochondrial dysfunction and oxidative stress play important roles in Alzheimer′s disease (AD). Isoliquiritigenin, a natural flavonoid isolated from the root of liquorice, has been shown to exert inhibitory effects on oxidative stress. Here, we assessed the neuroprotective effects of isoliquiritigenin on a streptozotocin-injected mouse model. Method Molecular docking analysis performed for isoliquiritigenin with mTOR and ERK2.
