Yuanying Chen
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Deletion of a YEDL sequence in SLC35D3 perturbs its targeting to platelet dense granule precursors
Key words Protein trafficking Adaptor protein complex BLOC-1 SLC35D3 Dense granules Introduction Dense granule (DG) is a type of lysosome-related organelles (LROs) specifically present in platelets. DG deficiency results in bleeding tendency, commonly observed in Hermansky-Pudlak syndrome (HPS) and Chediak-Higashi syndrome (CHS) (1). SLC35D3 is a nucleotide sugar transporter localized to synaptic vesicles (2).
Nonparametric two-sample test for random objects based on data depth
The rise of non-Euclidean data necessitates more versatile statistical tools. While two-sample testing is common, most existing methods are confined to specific data types or disparities. To address this gap, we propose an innovative, data depth-based two-sample test for random objects in metric spaces. We rigorously evaluate the test via simulation studies, examining its power and consistency against location and scale differences.
Hydrogen-Bonded Organic Framework Nanozyme with Multi-Enzyme Activity for Chemiluminescence Sensing of Acetylcholinesterase and Screening Its Inhibitors
Analytical Chemistry Cite this: Anal. Chem. 2025, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
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