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Apolipoprotein A-IV Has Bi-Functional Actions in Alcoholic Hepatitis by Regulating Hepatocyte Injury and Immune Cell Infiltration
Open AccessArticle by Wan-Hong Li 1,†, Li Zhang 1,†, Yue-Ying Li 1, Xin-Yue Wang 1, Jin-Liang Li 1, Shu-Ning Zhao 1, Ming-Qi Ni 1, Qian Li 2,* and Hui Sun 1,* 1 Pharmaceutical Experiment Teaching Center, College of Pharmacy, Harbin Medical University, Harbin 150081, China 2 Pharmaceutical Analysis and Analytical Chemistry, College of Pharmacy, Harbin Medical University, Harbin 150081, China * Authors to whom correspondence should be addressed. † These authors contributed equally to this work. Int.
A simple and rapid mix-and-read assay for sensitive detection of O6-methylguanine DNA methyltransferase
A simple and rapid mix-and-read assay for sensitive detection of O6-methylguanine DNA methyltransferase Ming-Hao Liu, Wan-tong Yu, Xiao-Yun Yang, Yue-Ying Li, Yan Zhang and Chun-Yang Zhang Abstract We develop a simple and rapid mix-and-read assay for sensitive detection of O6-methylguanine DNA methyltransferase (MGMT) activity based on exonuclease III-assisted signal amplification at absolutely isothermal conditions (37 °C).
Development of a phos-tag-based fluorescent biosensor for sensitive detection of protein kinase in cancer cells
Development of a phos-tag-based fluorescent biosensor for sensitive detection of protein kinase in cancer cells Protein kinase can catalyze the phosphorylation of peptides/proteins, and it is closely associated with various human diseases such as cancer, immune deficiencies, and Alzheimer’s disease. Sensitive monitoring of protein kinase activity is significant for biochemical research and drug discovery.
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