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Yuemao Shen on Muck Rack

Yuemao Shen

China
As seen in: Wiley Online Library, ACS Publications
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Articles

Synthesis of 2‐phenylnaphthalenoid amide derivatives and their topoisomerase IIα inhibitory and antiproliferative activities

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By Xiaoxia Wu, Chunhua Lu, Yuemao Shen, Guangsen Xu
| Wiley Online Library Verified
CONFLICTS OF INTEREST STATEMENT The authors declare no conflicts of interest. REFERENCES 1, , , , , , , , , J. Enzyme Inhib. Med. Chem. 2024, 39, 2302320. https://doi.org/10.1080/14756366.2024.2302920 2, , , , Nat. Rev. Mol. Cell Biol. 2022, 23, 407. https://doi.org/10.1038/s41580-022-00452-3 3, , , , Nat. Rev. Mol. Cell Biol. 2016, 17, 703. https://doi.org/10.1038/nrm.2016.111 4, , , Mol. Cell 2012, 45, 710. https://doi.org/10.1016/j.molcel.2012.03.001 5, , , J. Biol. Chem. 2005, 280, 39337.
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Discovery of 4,6-O-Thenylidene-β-d-glucopyranoside-(2″-acetamido, 3″-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4′-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K

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By Jie Cheng, Wei Zhao, Hui Yao, Yuemao Shen
| pubpeer.com
Comment Journal of Medicinal Chemistry (2020) - pubmed: 32084316 doi: 10.1021/acs.jmedchem.9b01354 issn: 0022-2623 issn: 1520-4804 Jie Cheng, Wei Zhao, Hui Yao, Yuemao Shen, Youming Zhang, Yue-zhong Li, Qingsheng QI, Kanokpan Wongprasert, Ya-Jie Tang
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Discovery of 4,6-O-Thenylidene-β-d-glucopyranoside-(2″-acetamido, 3″-acetyl-di-S-5-fluorobenzothizole/5-fluorobenzoxazole)-4′-demethylepipodophyllotoxin as Potential Less Toxic Antitumor Candidate Drugs by Reducing DNA Damage and Less Inhibition of PI3K

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By Jie Cheng, Wei Zhao, Hui Yao, Yuemao Shen
| ACS Publications
As an FDA-approved drug, teniposide, was utilized in cancer treatment but was accompanied by a strong side effect in long-term clinical trials. This work discovered potential candidate drugs with low toxicity by modifying the molecule structure of teniposide through a structure-guided drug design approach.
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