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Yusmel González-Hernández on Muck Rack

Yusmel González-Hernández

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Articles

Multi-omic characterization of antibody-producing CHO cell lines elucidates metabolic reprogramming and nutrient uptake bottlenecks

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By Patrick Perre, Pavlos Kotidis, Cleo Kontoravdi, Yusmel González-Hernández
| ScienceDirect Verified
Cell line engineering and process optimization are two major challenges faced by the bioprocessing industry in the quest to achieve sustainable production of high-quality products (Tihanyi and Nyitray, 2020). Because the development of engineered strains capable of achieving high product titers is time consuming and costly (Nielsen and Keasling, 2016), there is an imminent need to develop intelligent approaches to cell and process engineering to accommodate existing and emerging products.
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