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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
UHRF1 Supports PARP1 Protein Stability and Ovarian Cancer Progression by Limiting PARP1 Polyubiquitination
CHX cycloheximide CI confidence interval CPTAC Clinical Proteomic Tumor Analysis Consortium GO Gene Ontology HR hazard ratio IHC immunohistochemistry OS overall survival PARP1 poly (ADP-ribose) polymerase 1 PFS progression-free survival RNF4 ring finger protein 4 UHRF1 ubiquitin-like with PHD and RING finger domains 1 1 Introduction Ovarian cancer remains the most lethal gynecologic malignancy, in part because many patients present with advanced disease and subsequently develop recurrence or...
Transition shock and depression-anxiety-stress symptoms among nursing interns in China: the indirect roles of self-efficacy and burnout in a cross-sectional mediation and network analysis study
Abstract Background: Clinical internship is a high-risk period for psychological distress among nursing interns. Grounded in Conservation of Resources theory's resource loss spiral proposition, this study examined serial associational pathways via self-efficacy and burnout linking transition shock to depression-anxiety-stress symptoms and explored their symptom-level network structure.
Radiation regimes shape microbial light-harvesting strategies and network organization on glacier surfaces
Abstract Glacier cryoconite hosts metabolically active microbial communities despite exposure to solar radiation, which both provides energy and imposes stress. However, how radiation regimes are associated with microbial energy acquisition strategies and ecosystem organization remains unclear. Here, we analyzed 85 cryoconite metagenomes, including 47 from Arctic glaciers and 38 from Tibetan Plateau glaciers, representing contrasting long-term radiation environments.
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