Yuying Li
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Dissecting the shared genetic architecture and biological mechanisms linking sleep traits and suicide attempts: from variants to genes
Abstract Comorbidities and genetic correlations between sleep traits and suicide attempts suggest potential shared genetic architecture, but pleiotropic genetic variants and functions remain unclear. This study aimed to identify shared genetic variants, genes, and biological mechanisms linking sleep traits with suicide attempts. We conducted a genome-wide pleiotropic analysis using GWAS summary statistics for 11 sleep traits and suicide attempts.
Multi-Dimensional Tracing of Particulate Organic Matter Sources in a Deep-Water Reservoir: Coupling Temporal Dynamics, Water Depth Stratification, and Particle-Size Effects
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data supporting this study were generated via experiments funded by the corresponding author. As these constitute proprietary laboratory assets reserved for future research, they are not publicly archived.
Comprehensive analysis of miRNA expression, secretion profile, and functional network during myogenesis in response to spaceflight
Abstract MicroRNAs (miRNAs) are key regulators of skeletal muscle development and homeostasis. As secretory factors, previous studies have identified and validated a space flight-associated circulating microRNA (miRNA) signature in response to space flight. However, the muscle-derived miRNAs are not clear. Here, we comprehensively analyzed the variations of miRNA during mouse myoblast myogenesis in response to space flight, including expression and secretion.
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