Yuying Li
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Comprehensive analysis of miRNA expression, secretion profile, and functional network during myogenesis in response to spaceflight
Abstract MicroRNAs (miRNAs) are key regulators of skeletal muscle development and homeostasis. As secretory factors, previous studies have identified and validated a space flight-associated circulating microRNA (miRNA) signature in response to space flight. However, the muscle-derived miRNAs are not clear. Here, we comprehensively analyzed the variations of miRNA during mouse myoblast myogenesis in response to space flight, including expression and secretion.
Deciphering functional intra-tumoral heterogeneity in BRAF V600E -driven mouse thyroid cancer reveals EMT trajectory and metabolic remodeling
Abstract A better understanding of functional heterogeneity of tumor cells may lead to the improvement of the diagnosis and development of effective therapies for patients with papillary thyroid cancer (PTC). Here, the transcriptional heterogeneity and hierarchical trajectory of malignant thyrocytes were investigated by single-cell RNA sequencing analysis in an adult-onset autochthonous mouse model of PTC driven by a BRAFV600E.
Frontiers | Establishment and validation of a clinical prediction model for perioperative pneumonia in elderly patients with hip fractures combined with preoperative stroke
Abstract Background: Hip fractures in the elderly are associated with alarmingly high disability and mortality rates, which severely impair patients’ quality of life. Patients with a history of stroke face a significantly increased risk of perioperative pneumonia and a threefold higher risk of death. This study aimed to establish a clinical prediction model for perioperative pneumonia in elderly patients with hip fractures and preoperative stroke.
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