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Yuying Xie on Muck Rack

Yuying Xie

As seen in: Nature, Wiley Online Library, PLOS, Frontiers, MDPI, Science Magazine, BioRxiv, Dove Medical Press, Texas Medical Center, Genetics and
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Articles

Oral nano-delivery of a gut microbial metabolite enhances T cell stemness for cancer immunotherapy

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By Kai Han, Young Seok Cho, Mariko Takahashi, Xingwu Zhou, Hannah Dobson, Yuesong Wu, Youngseo Na, Fang Xie, Jinmei Wu, Jin Xu, Chuan Ping Lee, Himani Jasewicz, Yujin Kim, Minal Nenwani, Olamide Animasahun, Fulei Wuchu, Anthony Andren, Harrison Wong, Emma F. Camp Verified, Ziye Wan, Qi Wu, Li Zhang, Cheng Xu, Katherine X. Dong, Yao Xu, Anna Schwendeman, Grace Chen, Yuying Xie, Costas A. Lyssiotis, Martin Clasby, Deepak Nagrath, Yu Lei, James Moon, Kim Hutchings, Julia Crowther
| Nature Verified
Abstract Gut microbial metabolites play crucial roles in regulating systemic immunity, but their mechanisms and limited drug-like properties remain unresolved. Here we report an oral nano-formulation that leverages gut microbial metabolites to modulate T cell metabolism and amplify antitumour immunity.
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BATF2 is a glutamine-responsive tumour suppressor required for type-I interferon-dependent anti-tumour immunity - Nature Communications

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By Yuesong Wu, Xingwu Zhou, Xin Hu, Kohei Okuyama, Qiang Hu, Christopher R. Donnelly, Zhiqian Zhai, Mei Zhao, Jiaqian Li, Shadmehr Demehri, Deepak Nagrath, Andrew G. Sikora, Yanbao Yu, Haitao Wen, Lei Wei, Jeffrey Myers, Yuying Xie, James Moon, Arash Yunesi, Zackary R. Fitzsimonds
| Nature Verified
Abstract Recent evidence highlights the significance of a new type of tumour suppressors, which are not frequently mutated but inhibited by metabolic cues in cancers. Here, we identify BATF2 as a tumour suppressor whose expression is epigenetically silenced by glutamine in Head and Neck Squamous Cell Carcinomas (HNSCC). BATF2 correlates with type-I interferon and Th1 signatures in human HNSCC, with correlation coefficients even stronger than those of the positive control, STING.
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Honokiol‐based pH‐responsive amphiphilic polymer as an intelligent delivery system for rhizosphere‐targeted herbicide application

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By Yuying Xie, Yangchun Ge, Zhuochao Shen, Yupeng Qiu
| Wiley Online Library Verified
CONFLICT OF INTEREST The authors declare that they have no competing interests. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description ps70311-sup-0001-supinfo.docxWord 2007 document , 88.8 KB Figure S1. Nile Red standard curve graph. Table S1. Encapsulation efficiency and drug loading capacity of Nile Red at different polymer-to-drug ratios.
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