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Yuzhi Yin on Muck Rack

Yuzhi Yin

As seen in: Frontiers, The Journal of Allergy & Clinical Immunology
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Articles

ELK4 exerts opposite roles in cytokine/chemokine production and degranulation in activated mast cells

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By Wendy Watford, Yuzhi Yin, Gregorio Gomez
| Frontiers
Introduction Anaphylaxis is a serious allergic reaction that occurs rapidly and includes signs and symptoms that involve the skin, gastrointestinal tract, respiratory system, and cardiovascular system (1). Anaphylaxis can be caused by allergies to foods, insect venoms, medications, and other agents (1). The incidence of food-induced anaphylaxis has increased at an alarming rate, especially in children, over the past several decades and still continues to increase (2, 3).
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A role for GLI transcription factors in the proliferation and survival of human mast cells

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By Guido Falduto, Yuzhi Yin, Dean D. Metcalfe, Ana Olivera
| The Journal of Allergy & Clinical Immunology Verified
Glioma-associated (GLI) transcription factors play important roles in tissue homeostasis and the hematopoietic system by regulating differentiation, survival, and proliferation. Given that mast cells (MCs) accumulate in tissues in MC-related disorders, including allergy and mastocytosis, we sought to investigate a potential role for GLI proteins in the regulation of the proliferation and survival of human MCs (huMCs).
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Demonstration and implications of IL-3 upregulation of CD25 expression on human mast cells

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By Yuzhi Yin, Yun Bai, Ana Olivera
| The Journal of Allergy & Clinical Immunology Verified
This paper is only available as a PDF. To read, Please Download here. Abstract Background CD25+ human mast cells (huMCs) have been reported in patients with monoclonal mast cell diseases and in rare association with inflammation. However, the regulation of CD25 expression on huMCs and the possible biologic consequences remain poorly understood. Objective We sought to identify conditions which would up-regulate CD25 expression on huMCs and to explore possible functional implications.
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