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Zachary Freyberg on Muck Rack

Zachary Freyberg

Hamburg, Germany
As seen in: Nature, Frontiers, Science Magazine, BioRxiv, JNeurosci, JoVE- Journal of Visualized Experiments
Global Head of Communications, Media & Technology Practice at Kearney.
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Articles

Sexual dimorphism of midbrain catecholaminergic metabolism revealed by neuromelanin-sensitive MRI

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By Robert Raeder, Helmet T. Karim, Michele A. Bertocci, Yui Asaoka, Chan H. Moon, Manan Arora, Luke Roberts, Genna Bebko, Haris Aslam, Simona Graur, Megan Atkinson, Osasumwen Benjamin, Yiming Wang, Richelle Stiffler, Deepak K. Sarpal, Zachary Freyberg, Mary Phillips, Dominique DiDomenico
| Nature Verified
Abstract Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) is used as a proxy biomarker of midbrain catecholaminergic metabolism and synthesis capacity, particularly within dopaminergic nuclei. However, despite strong translational evidence for sexual dimorphism in dopaminergic systems, inconsistent sex differences in NM-MRI signal limit its interpretability as a non-invasive measure of catecholaminergic synthesis capacity.
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The molecular basis of mitochondrial crista formation by the MIC10 complex

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By Mads Peter Heide-Jørgensen, Fangbing Chen, Jeric Da-Anoy, Chelsea Brown, Tsjerk A. Wassenaar, Zachary Freyberg, Siewert J. Marrink
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share This article has 0 eLetter . Abstract Mitochondrial cristae are essential for respiration, yet the molecular basis of how the high curvature of these membrane folds is maintained remains unclear.
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Psychosis as a multisystem disorder of aberrant aging

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By Rachel Upthegrove, Antonio de Marvao, Benjamin Perry, Fabiana Corsi-Zuelli, Jack Rogers, Lahiru Handunnetthi, Nicholas Barnes, Nikolaos Koutsouleris, Paris A. Lalousis, Toby Pillinger, Zachary Freyberg, Amalie C. M. Couch
| Nature Verified
Abstract Psychotic disorders, including schizophrenia and affective psychosis, affect ~3% of the population and typically emerge in early adulthood. Cardiometabolic disease accounts for much of the 20-year life-expectancy gap in psychosis. Evidence indicates potentially causal processes, often seen in aging, act within and beyond the brain, and before the onset of treatment; these include inflammation, metabolic and mitochondrial dysfunction.
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