Zhao-Xia Liu

Inherently disordered N- and C-tails confer full helicase activities to the Dbp2 protein To probe the spatial conformation of N- and C-tails relative to the full-length Dbp2 in solution, SAXS assays were performed. Figure S6A is the experimental SAXS profile of Dbp2. The EOM ( ) analysis was carried out for Dbp2 by introducing flexibility in the N-and C-tails, and in the linker between the helicase core. An atomic model was finally obtained with χ 2of 1.62 (Fig. 5A).