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Zhiying Yao on Muck Rack

Zhiying Yao

As seen in: Nature, Wiley Online Library, MDPI, Taylor & Francis Online, Cell Press
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Articles

PARP10 condensation inhibits viral replication via targeting NAD + homeostasis

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By Xiaoxin Chen, Qi Xu, Yi Liu, Zhenshuo Zhu, Ziqiu Wang, Yun Zhang, Ziru Li, Qi Chen, Le Tian, Zhiying Yao, Youngdae Gwon, Zhubing Shi, Peiguo Yang, Yunan Mao, Chenmiao Ai
| Nature Verified
Abstract Although diphtheria toxin-like ADP-ribosyltransferases (ARTDs) are implicated in host-virus interactions, the specific antiviral mechanisms of certain family members remain largely undefined. Here, we reveal that mono-ADP-ribosyltransferase PARP10 restricts viral replication by forming biomolecular condensates via multivalent interactions among its structured domains.
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Self-Assembly of Antigenic Peptide Nanofibrils Templates the Growth of Silica Nanoparticles for Nanovaccines

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By Xuecheng Yang, Min Li, Zhiying Yao
| Wiley Online Library Verified
1 Introduction Peptide vaccines have been widely used in immunotherapy because of their high safety, biocompatibility, specificity, and structural design flexibility [1, 2], and have been applied in the treatment of neurodegenerative diseases, cancers, infectious diseases, and autoimmune diseases [3-6].
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Alphaviral non-structural protein-host RBP co-condensation as a mechanism to sustain virus replication

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By Yi Liu, Zhiying Yao, Yun Zhang, Zhenshuo Zhu, Ziqiu Wang, Qi Chen, Zemin Yang, Yexuan He, Xiaoxin Chen, Le Tian, Jiang Du, Jinjun Wu, Hong Joo Kim, Jing Huang, Yongdeng Zhang, Weirui Ma, Wenchun Fan, J. Paul Taylor, Peiguo Yang
| Cell Press Verified
ArticleVolume 86, Issue 12p2390-2409.e17 Affiliations & Notes 1Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China 2School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China 3Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, USA 4Howard Hughes Medical Institute, Chevy Chase, MD, USA 5Life Sciences Institute, Zhejiang University, Hangzhou, China Article Info Publication History: Received April 16, 2025;...
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