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Zhouchun Shang on Muck Rack

Zhouchun Shang

As seen in: Nature
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Articles

A single-cell transcriptome atlas of human euploid and aneuploid blastocysts - Nature Genetics

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By Yifan Gu, Longqi Liu, Huanming Yang, Xun Xu, Zhouchun Shang
| Nature Verified
Abstract Aneuploidy is frequently detected in early human embryos as a major cause of early pregnancy failure. However, how aneuploidy affects cellular function remains elusive. Here, we profiled the transcriptomes of 14,908 single cells from 203 human euploid and aneuploid blastocysts involving autosomal and sex chromosomes. Nearly all of the blastocysts contained four lineages.
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Dbh+ catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart - Nature Communications

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By Wei Hu, Ying Liu, Ao Chen, Zhouchun Shang, Lucile Miquerol, Nicola Smart, Henggui Zhang, Weinian Shou, Xianhong Ou, Xiaoqiu Tan
| Nature Verified
Abstract The heterogeneity of functional cardiomyocytes arises during heart development, which is essential to the complex and highly coordinated cardiac physiological function. Yet the biological and physiological identities and the origin of the specialized cardiomyocyte populations have not been fully comprehended. Here we report a previously unrecognised population of cardiomyocytes expressing Dbhgene encoding dopamine beta-hydroxylase in murine heart.
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