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ADORA1 inhibition suppresses colon cancer development via hippo tumor suppressor pathway

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By Zhongbo Li, Zhihao Liu, Xiaobo Zhang, Xiujie Cui, Xin Li Verified, jiayao Cui, Fangyu Shen, Yan Zhou, Pengzhao Song, Lin Ma, Hanxue Zhang, Haidi Hu, Ting Zhuang, Jian Zhu, Zhuocong Bao
| Nature Verified
Abstract Coffee is one of the most commonly consumed beverages in daily life, with caffeine being the major psychoactive component that acts against fatigue and drowsiness. Epidemiological studies have demonstrated the protective effect of coffee intake on colon cancer risk, recurrence and overall survival, but the detailed mechanisms are unclear.
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