Zhuoying Li

?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract Recommender systems (RSs) increasingly support self-regulated learning (SRL) through personalized resources, feedback, and strategy recommendations.

1 Introduction Lynch syndrome (LS) is an autosomal dominant hereditary cancer syndrome that accounts for approximately 1%–3% of newly diagnosed colorectal cancers (CRC) [1]. It is caused by pathogenic germline variants in the DNA mismatch repair (MMR) genes MLH1, PMS2, MSH2, and MSH6, as well as deletions involving EPCAM [2, 3]. The lifetime risk of CRC and other LS-associated cancers increases substantially in affected individuals and may reach 50%–80% [4].

Abstract Kawasaki disease (KD) is an acute systemic vasculitis that the primary cause of secondary heart disease in children. Dysregulation of microRNA (miRNA) expression drives gene expression patterns across multiple biological processes, thereby mediating the pathogenesis and progression of KD. This study investigated how miR-125a-5p regulates pyroptosis in KD-associated endothelial cells.