Ziadoon Alyaqoobi on Muck Rack

Ziadoon Alyaqoobi

As seen in: Dialnet - Universidad de La Rioja
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Articles

Single-cell and bulk transcriptome analysis reveals the impact of inflammatory microglia on prognosis and immunotherapy response in primary glioblastoma

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By Yin He, Xiaosheng Wang, Ziadoon Alyaqoobi
| Dialnet - Universidad de La Rioja
Background: Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis. Microglia are key immune cells in the GBM tumor microenvironment (TME), yet their subtype-specific impact, particularly inflammatory microglia, remains poorly understood. Methods: We analyzed single-cell RNA sequencing data to characterize inflammatory microglia patterns in GBM. Patient subgroups were compared for clinical features, molecular profiles, and predicted immunotherapy responses.
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