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Efficacy and safety of different immunosuppressive agents in patients with calcineurin inhibitor-dependent primary membranous nephropathy
Abstract Objective: To compare the efficacy and safety of rituximab (RTX), cyclophosphamide (CTX), and tripterygium glycosides (TII) as conversion therapies in patients with calcineurin inhibitor (CNI)–dependent primary membranous nephropathy (PMN), and to evaluate their ability to induce clinical and immunological remission and facilitate CNI withdrawal.
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis
Research Paper Volume 16, Issue 8 pp 7277—7292 1 The First Department of Nephrology, Cangzhou Central Hospital, Cangzhou, Hebei, China 2 Department of Hematology, Cangzhou Central Hospital, Cangzhou, Hebei, China https://doi.org/10.18632/aging.205756 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation: Citation | Copyright: © 2024 Zhang et al.
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis
Purpose: Medium-chained chlorinated paraffins (MCCPs) are a class of chlorinated derivatives of straight-chain n-alkanes with complex compositions, which are widely used in industry. The chlorinated paraffins (CPs) are divided into short chain chlorinated paraffins (SCCPs), medium chain chlorinated paraffins (MCCPs) and long chain chlorinated paraffins (LCCPs). SCCPs have been banned due to their severe bioaccumulation and biotoxicity.
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