Zongying Liang

Abstract Lung cancer has the highest incidence and mortality rates among all malignant tumors worldwide, with poor treatment outcomes and a high risk of postoperative recurrence. Currently, more than 50% of lung cancer cases are lung adenocarcinoma, which is characterized by early metastasis, recurrence, and therapeutic challenges. However, lung adenocarcinoma underlying nosogenesis mechanisms remain unclear.

1. Introduction Esophageal cancer is a common gastrointestinal tumor in the world, which has a high morbidity and mortality rate [1]. Although surgery, chemotherapy and radiotherapy have somewhat improved the prognosis of some patients with esophageal cancer, the overall survival rate remains unsatisfactory [2]. Modern medical research has found that the protein acetylation modification in epigenetics plays an important role in the occurrence and development of tumors [3] [4].