Zuzana Lásko

Introduction Click to copy section linkSection link copied! Lipidomics is a field dealing with the determination of lipids in biological systems at a defined time. Within this complex landscape, a group of lipids centered around a glycerol or sterol backbone plays fundamental roles in energy storage, membrane structure, and signaling pathways.

Extraction of Less Polar Lipids The main objective of this study was to develop a selective and efficient workflow for the extraction and analysis of less polar lipid classes from human plasma. Although these lipid species can be analyzed by using commonly applied chromatographic techniques, such approaches often introduce significant limitations when applied to this lipid group.

Introduction Click to copy section linkSection link copied! Lipids are essential components of all living organisms and play critical roles in cellular processes, such as energy storage, signaling, and formation of membrane structure. (1) Lipidomics is the study of the structure, function, and metabolism of lipids. The dysregulation of lipids has been linked to many diseases, such as hypercholesterolemia, (2,3) Alzheimer’s disease, (4) cardiovascular diseases, (5) and cancer.