Abby Dernburg

Stand Up For Science 2025 Announces National Day of Action: March 7, 2025 WHAT: A rally to defend science as a public good and central pillar of social progress. WHY: Science is for everyone-and benefits everyone. When the federal government supports scientific research through taxpayer funding, it fuels innovation, creates jobs, and sustains the world we live in.

Keywords cell biology AI ML virtual cell Introduction The cell, the fundamental unit of life, is a wondrously intricate entity with properties and behaviors that challenge the limits of physical and computational modeling. Every cell is a dynamic and adaptive system in which complex behavior emerges from a myriad of molecular interactions. Some aspects are remarkably robust to perturbations, such as the elimination of genes or their replacement with homologs from different species.

Editor’s summary Cells have a variety of mechanisms for monitoring the many steps involved in DNA replication and cellular reorganization during meiosis. Liu and Dernburg devised a chemically induced proximity approach based on a plant hormone–sensing pathway. They then used this method to demonstrate the role of polo-like kinase 2 in a mechanism that monitors the proper formation of synaptonemal complexes between homologous chromosomes during meiosis.