Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Get in touch with Adele A.
Contact Adele A., search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck RackActions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
UL34 Deletion Restricts Human Cytomegalovirus Capsid Formation and Maturation
Open AccessArticle by Declan L. Turner 1, Rachel M. Templin 2, Adele A. Barugahare 1,3, Brendan E. Russ 1, Stephen J. Turner 1, Georg Ramm 2,4 and Rommel A.
Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate
Lauren J. Howson, Jasmine Li, Anouk von Borstel, Adele Barugahare, Jeffrey Y. W. Mak, David P. Fairlie, James McCluskey, Stephen J. Turner, Martin S. Davey and Jamie Rossjohn J Immunol April 1, 2021, 206 (7) 1425-1435; DOI: https://doi.org/10.4049/jimmunol.2001048 Key Points MAIT cells have varying capacities to produce effector cytokines when activated. MAIT cells have transcriptional signatures associated with early effector function.
KDM6B-dependent chromatin remodeling underpins effective virus-specific CD8+ T cell differentiation
Highlights • Naive CD8+ T cell activation results in chromatin changes prior to first cell division • The H3K27me3 demethylase KDM6B is rapidly upregulated upon T cell activation • H3K27me3 demethylation occurs in a stepwise manner ensuring optimal T cell activation • Perturbation of KDM6B function results in suboptimal virus-specific CD8+ T cell memory Summary Naive CD8+ T cell activation results in an autonomous program of cellular proliferation and differentiation.
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Adele A.
Contact Adele A., search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack