Aiming Zhou

1 Introduction Sepsis is a fatal organ dysfunction caused by an uncontrolled host response to infection and is associated with high morbidity and mortality worldwide.[1] According to two independent cohorts, sepsis accounts for one in every two to three deaths in terms of overall hospital mortality.[2] In a 2020 report in The Lancet, there were an estimated 48.9 million cases of sepsis worldwide every year and ≈11.0 million deaths from sepsis.[3] Notably, more than half of septic patients...

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