Jun Yin
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
ISGylation-mediated stabilization of CYP4Z1 fuels breast cancer initiation and progression
Abstract Tumor-initiating cells (TICs) are central to cancer progression and metastasis; however, they remain challenging to target therapeutically. Here, using a breast-specific CYP4Z1-transgenic MMTV-PyMT mouse model, we show that CYP4Z1 notably accelerates tumor initiation, enlarges tumor size, promotes metastasis, and expands TIC populations. Multi-omics analyses reveal that CYP4Z1+ epithelial cells exhibit enhanced stemness and reduced differentiation compared with CYP4Z1− counterparts.
Nanoscale amorphization of poly(triarylamine) for efficient and stable inverted perovskite photovoltaics
Abstract Perovskite solar modules require hole-selective layers that combine efficient charge extraction, interfacial uniformity and scalable processing. Poly(triarylamine) (PTAA) is widely used in high-performance inverted perovskite photovoltaics, but its nanoscale crystallization and aggregation on indium tin oxide can disrupt film continuity, increase interfacial recombination and limit module stability.
Hydroxyl-rich nanocavities on perovskite enable nearly barrierless intramolecular hydrogen transfer for nitrate electroreduction to ammonia
Abstract Electrocatalytic nitrate reduction to ammonia (NITRR) provides a sustainable avenue for simultaneous nitrate mitigation and ammonia synthesis, but the sluggish surface hydrogen migration during NITRR remains a major bottleneck. Here, we show a barrierless hydrogen transfer pathway along intramolecular hydrogen bonds between hydroxyls of hydroxyl-rich nanocavities for efficient nitrate electroreduction to ammonia.
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