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Alberico Di Pinto

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Articles

AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma

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By Irene Basili, Francesca Bufalieri, Marilisa Conenna, Shirin Navacci, Yue-Ru Li, Jacob Torrejon, Flavia Bernardi, Ludovica Lospinoso Severini, Véronique Marsaud, Gabriele Cancila, Guillaume Bourmeau, Hua Yu, Valentina Re, Julie Talbot, Gennaro Adabbo, Daniela Giovannini, Simona Leonardi, Rosa Bordone, Marialaura Petroni, Judith Souphron, Thomas Blauwblomme, Kévin Beccaria, Christelle Dufour, Luca D’Angelo, Enrico De Smaele, Gianluca Canettieri, Giuseppe Giannini, Gian Maria Fimia, Marella Maroder, Daniele Guardavaccaro, Simonetta Pazzaglia, Jin-Wu Tsai, Paola Páez Infante, Olivier Ayrault, Lucia Di Marcotullio, Alberico Di Pinto, Francesca Agnoli
| Cell Press Verified
Keywords AMBRA1 sonic hedgehog pathway pediatric cancer medulloblastoma ubiquitylation transcriptomics proteomics Introduction Autophagy and beclin 1 regulator 1 (AMBRA1) is an intrinsically disordered protein that plays a crucial role in various physiological processes.1,2 AMBRA1 exhibits exceptional adaptability, serving as a versatile scaffold protein implicated in autophagy, embryogenesis, early nervous system development, proliferation, as well as in pathological events including...
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