Yue-Ru Li

Keywords AMBRA1 sonic hedgehog pathway pediatric cancer medulloblastoma ubiquitylation transcriptomics proteomics Introduction Autophagy and beclin 1 regulator 1 (AMBRA1) is an intrinsically disordered protein that plays a crucial role in various physiological processes.1,2 AMBRA1 exhibits exceptional adaptability, serving as a versatile scaffold protein implicated in autophagy, embryogenesis, early nervous system development, proliferation, as well as in pathological events including...