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Articles

Disaster Recovery Tabletop Exercise: A CIO's Step-by-Step Guide

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By Alex Kim
| bcs365.com
A well-designed Disaster Recovery Tabletop Exercise can expose critical gaps in your incident response plan before a real crisis hits. Most disaster recovery plans stay on the shelf until an emergency makes their flaws obvious. Running a structured tabletop exercise helps you find these gaps while the stakes are low. A Disaster Recovery Tabletop Exercise is a structured, discussion-based simulation where key personnel meet to walk through an emergency scenario.
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Treatment Delays in Early Age–Onset Colorectal Cancer

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By Ryan Heslin, Zachary Whitham, Morgan F. Pettigrew, Gilbert Murimwa, Lauren Tyler, Matthew R. Porembka, Patricio M. Polanco, Herbert J. Zeh, Adam C. Yopp, Cecilia G. Ethun, Sam Wang, Alex Kim, Leah W. Ding
| JAMA Oncology Verified
Key Points Question What are the demographic and clinical patterns in early age–onset colorectal cancer (EOCRC) that determine poor outcomes in a heterogeneous population? Findings In this population-based cross-sectional study of 112 672 patients with colorectal cancer in Texas, 12 079 (11%) of whom had EOCRC, patients with EOCRC were more likely to be Hispanic, have left-sided or rectal tumors, and present with advanced-stage disease.
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Molecular phenotypes and spatial archetypes: A new framework for cancer-associated fibroblasts

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By Yunhe Liu, Xiongfeng Chen, Yibo Dai, Yiyue Jia, Yann Kieffer, Luyu Xie, Zhuan Zhou, Lauren Tyler, Alex Kim, Giulia Biffi, Akshay T Krishnamurty, Fatima Mechta-Grigoriou, Ruth Scherz-Shouval, Mara Sherman, Shannon J. Turley, Linghua Wang, Huocong Huang
| Cell Press Verified
Keywords cancer-associated fibroblasts tumor microenvironment stroma stroma-targeted therapy Introduction Fibroblasts were first identified by Rudolf Virchow in 1858 and named by Ernst Ziegler in 1881 to reflect their role in producing connective tissue during wound healing. In healthy organs, they maintain extracellular matrix (ECM) homeostasis, define structural boundaries between parenchyma and stroma, and serve as dynamic first responders that orchestrate wound repair.
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