Skip to main content
Alexander Ying on Muck Rack

Alexander Ying

As seen in: Science Magazine, BioRxiv, Cell Press, Managing Intellectual Property
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Alexander

Contact Alexander, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform

|
By Guoyan Luo, Subo Dong, SIDDHANT JAIN, Kaylyn E. Williamson, Alexander Ying, Shaunak Raval, Kevin So, Maxwell Allison, Akshay Sankar, Yutong Lin, Zhe Jiang, Nazar Mashtalir, Cheryl F. Lichti, Kaylyn E. Williamson, Aasha M. Turner, Ruidong Jerry Jiang, Henry W. Rohrs
| Science Magazine Verified
Abstract Mammalian SWI/SNF chromatin remodeling complexes modulate DNA accessibility and gene expression; however, their genomic targeting mechanisms remain incompletely understood. Here, we identify SWIFT (SWI/SNF Ig-fold for transcription factor interactions), a conserved transcription factor (TF) binding platform on the SMARCD subunits.
Open in Who Shared Issue with article?

Molecular grammars of predicted intrinsically disordered regions that span the human proteome

|
By Kiersten M. Ruff, Matthew King, Alexander Ying, Vicky Liu, Avnika Pant, Whitney E. Lieberman, Min Kyung Shinn, Xiaolei Su, Cigall Kadoch, Rohit V. Pappu
| Cell Press Verified
Keywords intrinsically disordered regions molecular grammars subcellular localization biomolecular condensates transcriptional regulation RNA polymerase cancer Introduction Eukaryotic proteomes are composed of proteins with folded domains1 and intrinsically disordered regions (IDRs).2,3,4,5,6,7,8 IDRs are implicated in a range of molecular functions and cellular processes.3,9,10,11,12,13,14 The amino acid alphabet is used in a biased manner,8,9,10 and a subset of this non-random alphabet is...
Open in Who Shared Issue with article?

Molecular grammars of intrinsically disordered regions that span the human proteome

|
By Kiersten M. Ruff, Matthew King, Alexander Ying, Vicky Liu
| BioRxiv
Abstract Intrinsically disordered regions (IDRs) of proteins are defined by functionally relevant molecular grammars. This refers to IDR-specific non-random amino acid compositions and non-random patterning of distinct pairs of amino acid types. Here, we introduce GIN (Grammars Inferred using NARDINI+) as a resource, which we have used to extract the molecular grammars of all human IDRs and classified them into thirty distinct clusters.
Open in Who Shared Issue with article?
See all 6 licensed articles (7 Total)