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Ali Azarbarzin on Muck Rack

Ali Azarbarzin

As seen in: Color Research & Application, Nature, Wiley Online Library, Thorax, JAMA Network, Healio Pulmonology, European Respiratory Journal, Texas Medical Center, Chest
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Articles

Hypoglossal Nerve Stimulation and Hypoxic Burden in Patients With Obstructive Sleep Apnea : A Secondary Analysis of the STAR Trial

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By Jing Xu, Mark S. Aloia, Olivier Vanderveken, Phillip Huyett, Ryan J. Soose, Raj Dedhia, Patrick J. Strollo, Ali Azarbarzin, Zohreh Hajipour, Sara Op de Beeck
| JAMA Network Verified
Hypoglossal Nerve Stimulation and Hypoxic Burden in Patients With Obstructive Sleep Apnea: A Secondary Analysis of the STAR Trial Key Points Question Is hypoglossal nerve stimulation (HGNS) associated with reduced hypoxic burden in patients with obstructive sleep apnea? Findings This secondary analysis of the Stimulation Therapy for Apnea Reduction trial included 108 adults and found that HGNS was associated with a 76.6% reduced hypoxic burden and improvements in daytime sleepiness.
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Tirzepatide on obstructive sleep apnea-related cardiometabolic risk: secondary outcomes of the SURMOUNT-OSA randomized trial - Nature Medicine

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By Ali Azarbarzin, Louis J. Aronne, Jitong Lou, Sujatro Chakladar, Mathijs C. Bunck
| Nature Verified
Abstract Obstructive sleep apnea (OSA) is associated with obesity and cardiovascular risk. The SURMOUNT-OSA master protocol comprised two, 52-week, randomized, double-blind, placebo-controlled phase 3 studies (study 1 and study 2) and demonstrated a significant reduction of a number of cardiometabolic risk measures in participants with OSA and obesity following treatment with tirzepatide. Here we report prespecified analysis of cardiometabolic risk measures in SURMOUNT-OSA.
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The hypoxic ventilatory response and arousal burden predict the magnitude of ventilatory long‐term facilitation in humans with obstructive sleep apnoea

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By Jason H. Mateika, Dylan Kissane Verified, Ali Azarbarzin, Danny Hammo
| Wiley Online Library Verified
1 INTRODUCTION Exposure to mild intermittent hypoxia during wakefulness elicits multiple forms of respiratory plasticity in humans, including progressive augmentation (PA) of the hypoxic ventilatory response and ventilatory long-term facilitation (vLTF) (Mateika & Narwani, 2009; Puri, Panza et al., 2021).
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