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Harmonized outcome measures for use in asthma patient registries and clinical practice
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig 1 The OMF, as completed for asthma characteristics and outcomes. The OMF depicts the minimum set of outcome measures recommended by the workgroup (right column), as well as the key characteristics of the participant, disease, and provider that should be captured to support risk adjustment (left column). Treatments of interest are listed in the center column.
A Randomized, Placebo-controlled, Double-blinded, Crossover Trial of Pioglitazone for Severe Asthma
Publication HistoryPublished online: June 15, 2017Accepted: May 12, 2017; Received in revised form: April 14, 2017; Received: February 7, 2017;
The A’s have it: Developing Apolipoprotein A-I Mimetic Peptides into a Novel Treatment for Asthma
New treatments are needed for asthmatics who are refractory to standard therapies, such as individuals with a phenotype of “type 2 low” inflammation. This important clinical problem could potentially be addressed by the development of apolipoprotein A-I (apoA-I) mimetic peptides. Apolipoprotein A-I interacts with its cellular receptor, the ATP-binding cassette subfamily A, member 1 (ABCA1), to facilitate cholesterol efflux out of cells to form nascent HDL particles.
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