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Andre Barbosa

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Articles

SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia - Nature Communications

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By Tomoyo Sawada, Arthur S. Feltrin, Yanhong Wang, Bruno Araujo, Bruno Araújo, Hunter Giles, Shizhong Han, Eugenia Radulescu, Andre Barbosa, Ricardo S. Jacomini, Violeta Dimitrova, Vladimir Vladimirov, Joel E. Kleinman, Thomas Hyde, Daniel R. Weinberger
| Nature Verified
Abstract Rare loss-of-function (LoF) mutations in SETD1A are associated with schizophrenia (SCZ). However, how SETD1A haploinsufficiency leads to SCZ-associated phenotypes and its relevance to patients without these rare mutations is unknown. Here, we identify SETD1A bound loci and regulated genes in human prenatal cortex and isogenic pluripotent stem cell-derived neuronal models engineered with SETD1A LoF variants, including the most common patient mutation.
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🕷️ Spider Manãƒ"Free 3MF File for 3D printingãƒ"Cults

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By Andre Barbosa
| Cults 3D
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Shake-Table Testing of a Full-Scale Six-Story Resilient Mass Timber–Steel Hybrid Building | Journal of Structural Engineering | Vol 151, No 12

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By Andre Barbosa, Steve Pryor, Barbara Simpson, Tanner Field
| ascelibrary.org
Data Availability Statement The data that support the findings of this study is available within the DesignSafe repository with project ID PRJ-5736 (Barbosa et al. 2025).
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