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HCN channels reveal conserved and divergent physiology in supragranular pyramidal neurons in primate species - Communications Biology

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By Cristina Radaelli, Matthew Schmitz, Xiao-Ping Liu, Ximena Opitz-Araya, Mark Hudson, Naz Taskin, Darren Bertagnolli, Jeff Goldy, andrew ko, Benjamin L. Grannan, Jason S. Hauptman, Anoop P. Patel, Charles Cobbs, Kimberly Smith Verified, William Spain, Ed Lein, Trygve E. Bakken, Nikolai C. Dembrow, Jonathan T. Ting, Scott Sawchuk
| Nature Verified
Abstract The physiological properties of human and rodent neurons differ, yet the extent to which these differences reflect human specializations is often unclear. Compared with their rodent counterparts, human supragranular pyramidal neurons possess enriched Hyperpolarization-activated Cyclic Nucleotide-gated channel (HCN channel)-dependent intrinsic membrane properties and a related sensitivity to synaptic inputs containing delta/theta band frequencies.
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OIG Approves Telehealth Arrangement for Leased Employees

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By David M. Traskey, andrew ko
| garfunkelwild.com
The U.S. Department of Health and Human Services, Office of Inspector General (OIG), recently issued a favorable Advisory Opinion (25-03) regarding a proposed arrangement (Arrangement) where a non-clinical management support organization and an affiliated professional corporation wholly owned by physician shareholders (PC) enters into lease agreements with telehealth platforms (Platforms) and providers employed by or contracted with these Platforms (Platform Providers).
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A New Look for DOJ White Collar Enforcement

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By John Martin Verified, David M. Traskey, andrew ko
| garfunkelwild.com
The U.S. Department of Justice, Criminal Division (DOJ) recently and unexpectedly announced changes to the manner in which it handles criminal investigations and prosecutions of white-collar and corporate cases. These changes are aimed at clarifying DOJ’s criminal enforcement priorities, increasing the efficiency with which cases are investigated and resolved, and emphasizing the benefits of voluntarily self-disclosing potential misconduct.
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