Annelien Morlion on Muck Rack

Annelien Morlion

As seen in: Nature, MDPI, Cell Reports, EOS Wetenschap
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Articles

Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls - Communications Medicine

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By Annelien Morlion, Philippe Decruyenaere, Jasper Anckaert, Justine Nuytens, Eveline Vanden Eynde, Kimberly Verniers, Celine Everaert, Guy G. Brusselle, Steven Callens, Filomeen Haerynck, Dimitri Hemelsoet, Eric Hoste Verified, Jo Lambert, Nicolaas Lumen, Fritz Offner, Koen Paemeleire, Vanessa Smith, Jo Van Dorpe, Amber Vanhaecke, Hans Van Vlierberghe, An Mariman, Olivier Thas, Jo Vandesompele, Pieter Mestdagh, Kathleen Schoofs, Nickolas Johns Ramirez, Lies Van den Eynde
| Nature Verified
Abstract Circulating nucleic acids in blood plasma form an attractive, minimally invasive resource to study human health and disease. In this study, we aimed to identify cell-free RNA alterations that can distinguish cancer patients from cancer-free individuals. We first performed mRNA capture sequencing on 266 blood plasma samples from cancer patients and controls, including a discovery set of 208 donors across 25 cancer types and a replication set of 58 donors across three cancer types.
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The road to discovery - a collaborative effort towards new insights in blood plasma RNA profiling

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By Annelien Morlion
| Nature Verified
Our exRNAQC study clarifies the impact of blood collection and processing variables on extracellular RNA (exRNA), or cell-free RNA (cfRNA), analysis.
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Wat onze lichaamssappen ons vertellen

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By Anneleen Decock, Annelien Morlion
| EOS Wetenschap Verified
Bloed is het lichaamssap bij uitstek voor het opsporen en opvolgen van ziektes. Het meten van het suikergehalte bij mensen met diabetes is een bekend voorbeeld. Een bloedonderzoek biedt een schat aan informatie die veel verder reikt dan wat er nu standaard gecontroleerd wordt. Bloed bevat namelijk ook andere moleculen die ons waardevolle inzichten kunnen bieden over onze gezondheid. Een fascinerend voorbeeld hiervan is celvrij RNA.
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