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Anto Pavlovic

As seen in: Nature, BioRxiv, Cell Press
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Articles

Foamy microglia link oxylipins to disease progression in multiple sclerosis

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By Xinyu Di, Tatiana M. Shamorkina, Anto Pavlovic, Yingyu Zeng, Will Macnair, J. Chen, Hendrik J. Engelenburg, Dennis D. Wever, Berend Gagestein, Elise Dusseldorp, Marco van Eijk, Uwe Grether, Amy C. Harms, Thomas Hankemeier, Ludovic Collin, Albert J. R. Heck, Inge Huitinga, Daan van der Vliet, Claire Coulon-Bainier, Iris A. C. M. van der Vliet, Noëlle van Egmond, Aletta M. R. van den Bosch, Wouter P. F. Driever, Mario van der Stelt
| Nature Verified
Abstract Multiple sclerosis (MS) is a chronic neuroinflammatory disease in which demyelinating white matter lesions accumulate and expand, driving irreversible disability. Here we identify a distinct population of foamy GPNMB+ microglia/macrophages associated with lesion expansion in secondary progressive MS.
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Foamy microglia link oxylipins to disease progression in multiple sclerosis

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By Xinyu Di, Tatiana M. Shamorkina, Anto Pavlovic, Yingyu Zeng
| BioRxiv
Abstract Multiple sclerosis (MS) is a neuroinflammatory disease characterized by expanding demyelinating lesions, leading to severe and irreversible disability. The mechanisms driving lesion expansion, however, remain poorly understood. Here, using a multi-omics approach, we identified foamy microglia as primary contributors to the molecular profile of lesions and disease progression in secondary progressive MS.
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High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

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By Dunja Mrdjen, Anto Pavlovic, Felix J. Hartmann, Bettina Schreiner
| Cell Press Verified
In the version of this paper published online, the URLs provided for the author-deposited data was incorrect. In the STAR Methods Key Resources Table, the entries in the section “Deposited Data” have been changed as shown below.
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