Antonio Gasbarrini
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Letter: Personalised FODMAP Modulation in IBS—Towards Less Restrictive Dietary Care
Dear Editor, We read with interest the randomised trial by Garcia-Cedillo et al. comparing a personalised FODMAP strategy with National Institute for Health and Care Excellence (NICE) dietary advice in irritable bowel syndrome (IBS) [1]. The authors address a timely question—how dietary care might evolve from standardised protocols towards more feasible, patient-centred approaches. They do so using data from Mexico, a setting underrepresented in IBS dietary research.
Klebsiella genus as driver of human disease: from infections to non-communicable disorders
Abstract Klebsiella spp. are pathobionts associated with acute infections, including pneumonia and infections in the urinary tract and bloodstream, often acquired in health-care settings. They represent a global threat owing to the prevalence of multidrug-resistant strains. Moreover, Klebsiella spp., similarly to other members of the human gut microbiota, can contribute to the pathogenesis of non-communicable disorders.
Poliprotect in the PPI Deprescription Phase of Endoscopy-Negative Heartburn and Epigastric Pain Syndrome Patients: An RCT Post Hoc Analysis
1 Introduction Proton pump inhibitors (PPIs) are widely prescribed for upper gastrointestinal symptoms and are among the most frequently used medications in chronic polypharmacy, particularly in older adults [1-5]. A substantial proportion of PPI prescriptions lack a clear long-term indication [6], even within healthcare institutions, raising concerns regarding safety, costs, and appropriateness [7-9].
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