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Articles by Athanasios Zouzos
Individualised progesterone receptor modulator prevention strategies for triple-negative breast cancer in BRCA1 pathogenic variant carriers
Abstract Women with germline BRCA1 pathogenic variants face a very high risk of early-onset triple-negative breast cancer (TNBC), with risk-reducing mastectomy currently the only established preventive option. Emerging evidence suggests aberrant progesterone signalling contributes to TNBC risk, while preclinical studies indicate progesterone receptor modulators such as mifepristone may substantially reduce cancer development.
Neoadjuvant palbociclib and endocrine therapy versus chemotherapy in ER + /HER2- breast cancer: a randomized phase II trial
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Abstract In PREDIX LumB patients with estrogen receptor positive and human epidermal growth factor receptor negative (ER + /HER2-) breast cancer > 20 mm and/or with lymph node metastasis were randomized 1:1 to receive either paclitaxel weekly for 12 weeks followed by palbociclib and endocrine therapy for 12 weeks (arm A), or the reverse sequence (arm B).
By Alexios Matikas, Michail Sarafidis, Emmanouil Sifakis, Judith Bjöhle, Elin Barnekow, Sara J. Margolin, Athanasios Zouzos, Hemming Johansson, Mats Hellström Verified, Per Grybäck, Ioannis Zerdes, Kang Wang, Johan Hartman, Balazs Acs, Wenwen Sun, Ceren Boyaci, Guillermo Villacampa, Tomás Pascual, Joaquín Gavilá, Aleix Prat, Charles M. Perou, Yvonne Brandberg, Jonas Bergh, Thomas Hatschek, Theodoros Foukakis, Evangelos Tzoras, Erika Isaksson-Friman, Luisa Edman Kessler, Susanne Agartz, Dimitrios Salgkamis
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Nature
Verified
Variation in Pathological Appearance Across Repeated Sampling from Probably Benign Breast Lesions
Submitted: 30 October 2025 You are already at the latest version Background The diagnostic process of probable benign breast lesions involves a 1–40% upgrade rate to malignancy comparing biopsy (cytology and/or histology) to surgery. Within a previous performed clinical randomized trial, we aimed to examine the diagnostic discrepancies between prior biopsy results and subsequent vacuum-assisted excision (VAE).
Magseed Application for Detecting Recurrent Lymph Node Metastasis in Papillary Thyroid Cancer: A Novel Minimally Invasive Approach
Papillary thyroid cancer is associated with lymph node metastasis and tumor recurrence that need repeated surgery, entailing surgical challenges with a high risk of complications such as nerve damage and bleeding. Magseed is a metal coil used to detect non-palpable lesions and is an established modality in breast cancer surgery. In this case series, we explore the feasibility of Magseed in metastasis surgery of papillary thyroid cancer.
Development of a new biopsy device for breast cancer
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