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Auginia Natalia on Muck Rack

Auginia Natalia

As seen in: Nature, Science Magazine, Cell Press
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Articles

Catalytic profiling of extracellular vesicles maps altered cancer metabolism

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By Qingchang Chen, Yan Zhang, Auginia Natalia, Jun L Zhou, Zhonglang Yu, Xianguang Ding, Chin-Ann J Ong, Jimmy So, Huilin Shao
| Nature Verified
Abstract Current technologies for measuring cancer metabolism have limited clinical utility, as they require invasive tissue sampling and lack analytical versatility. Here, we report a programmable nanotechnology platform that directly profiles extracellular vesicles (EVs) in patient biofluids to comprehensively capture metabolic alterations within the tumour milieu.
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Magnetic augmentation through multi-gradient coupling enables direct and programmable profiling of circulating biomarkers - Nature Communications

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By Li Zhang, Xingjie Wu, Noah R. Sundah, Auginia Natalia, Darren Lim, Carol Tang
| Nature Verified
Abstract Conventional magnetic biosensing technologies have reduced analytical capacity for magnetic field dimensionality and require extensive sample processing. To address these challenges, we spatially engineer 3D magnetic response gradients for direct and programmable molecular detection in native biofluids.
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Bidirectional linkage of DNA barcodes for the multiplexed mapping of higher-order protein interactions in cells - Nature Biomedical Engineering

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By Yu Chi Liu, Noah R. Sundah, Wan Shen, Auginia Natalia, Zhonglang Yu, Brian Lim
| Nature Verified
Abstract Capturing the full complexity of the diverse hierarchical interactions in the protein interactome is challenging. Here we report a DNA-barcoding method for the multiplexed mapping of pairwise and higher-order protein interactions and their dynamics within cells.
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