Barbara Slusher
Kingsville
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Resilient pathways for drug discovery in challenging times
Science & Society | Special issue: Advancing drug discoveryOnline now 1Collaborations Pharmaceuticals, Inc., Raleigh, NC 27606, USA 2Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA 3Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, USA 4Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA 5Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore,...
The potential of academic drug discovery: successes and challenges
Keywords: Academic Drug Discovery Centers (ADDCs) early-stage translational research industry-academia partnerships diversified funding emerging drug discovery technology challenging targets underserved therapeutic areas small molecules aI-based drug discovery 1.
24. Selective Inhibition of Microglial Glutaminase to Treat Chronic Stress-Induced Depression
Major depressive disorder (MDD) is a debilitating psychiatric condition with high treatment resistance, highlighting the need for new therapeutic targets. Glutaminase (GLS1), upregulated in activated microglia, has been implicated in MDD’s pathophysiology. This study evaluates dendrimer-based GLS1 inhibitors, D-TTM020 and D-JHU29, designed to selectively target microglial GLS1, in a Chronic Social Defeat Stress (CSDS) mouse model.
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