Barbara Steigenberger
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Metabolic Profiling of the EmDia Cohort by LC‐MS Reveals Empagliflozin‐Intake Associated Regulation of 1,5‐anhydroglucitol and Urate
1 Introduction Diabetes mellitus affects more than 500 million people worldwide. Type 2 diabetes mellitus (T2DM) makes up over 95% of all diabetes cases, and we face an ever-increasing prevalence, primarily caused by increasing obesity rates [1]. It is expected that T2DM will remain a major global epidemical burden [2] and T2DM patients often suffer from comorbidities, most prominently cardiovascular disease (CVD), [3] being a leading cause of morbidity and mortality in patients with T2DM [4].
Efficient Tandem Copper‐Catalyzed Click Synthesis of Multisugar‐Modified Oligonucleotides
Introduction Click chemistry is defined as a highly efficient method that allows the linking of two molecules in a short period of time, with high yields and with minimal formation of undesired side products.1, 2 This is particularly important for linking chemical entities to biomolecules because biomolecules are typically only available in small quantities and are often highly sensitive towards harsh reaction conditions.
Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions
Fabien Bonneau1, Jérôme Basquin1, Barbara Steigenberger2, Tillman Schäfer3, Ingmar B.
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