Barry Bruce

Significance The TOC-TIC system mediates the import of thousands of nuclear-encoded proteins into chloroplasts, essential for photosynthesis and plant growth. Toc34, a membrane-anchored GTPase receptor, regulates this gateway through oligomerization and nucleotide cycling. Using single-molecule photobleaching, FRET, and cross-linking, we directly visualized Toc34’s conformational heterogeneity and dynamic switching.

The Ottawa Civic hospital campus is poised to expand massively from its current (nearly) 600 beds to more than 1,200 beds. I have no particular quarrel with the cost ($2.8 billion) or the location (Central Experimental Farm). However, there is excellent evidence that such large hospitals are significantly inefficient, the optimal size being 200-to-300 beds.

The Civic campus will grow from about 600 beds to more than 1,200. I would suggest that it is a mistake to put so many health-care eggs in one basket. Author of the article: Dr. Barry Bruce The current Civic hospital campus. Its new version down the street will be huge. Photo by Tony Caldwell /Postmedia Article content The Ottawa Civic hospital caampus is poised to expand massively from its current (nearly) 600 beds to more than 1,200 beds.