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Barry Halliwell on Muck Rack

Barry Halliwell

As seen in: Color Research & Application, Nature, Wiley, MDPI, Royal Society of Chemistry
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Articles

Ergothioneine as a Protective Agent Against Age- Related Diseases: Issues Needing More Research

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By Barry Halliwell
| preprints.org
This version is not peer-reviewed. You are already at the latest version Ergothioneine (ET) is a diet-derived compound that is avidly absorbed and retained by the human body using a specialised transporter, OCTN1. A substantial and growing body of evidence implicates ET in maintaining human health and protecting against age-related diseases, especially neurodegenerative diseases, and multiple studies indicate that low blood ET levels increase the risk of developing age-related diseases.
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Ergothioneine as a potential protective agent against macular degeneration and other eye disorders

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By Irwin K. Cheah, Lucrecia Chen, Richard Tang, Lei Zhou, Yasuo Yanagi, Ching-Yu Cheng, Xinyi Su, Xueying Li, Tien-En Tan, Barry Halliwell, Zachary WeiJie Fong
| Nature Verified
Abstract Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in ageing populations, with oxidative stress recognised as a key pathogenic driver. The dietary antioxidant and cytoprotectant, L-ergothioneine (ET), is avidly accumulated in many tissues, especially the eye. However its relationship to AMD is unclear. Here, we examined ET’s distribution in human ocular tissues and measured serum and intraocular ET levels in patients with neovascular AMD.
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Ergothioneine Mediated Neuroprotection of Human iPSC derived-Dopaminergic Neurons.

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By Yang NG, Barry Halliwell, Lucrecia Chen, Wei Yi Ong
| preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 3 May 2024 / Approved: 7 May 2024 / Online: 7 May 2024 (11:48:13 CEST) Leow, D.M.K.; Cheah, I.K.M.; Chen, L.; Ng, Y.K.; Yeo, C.J.J.; Halliwell, B.; Ong, W.Y. Ergothioneine Mediated Neuroprotection of Human iPSC derived-Dopaminergic Neurons.. Preprints 2024, 2024050382.
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