Lucrecia Chen

Abstract Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in ageing populations, with oxidative stress recognised as a key pathogenic driver. The dietary antioxidant and cytoprotectant, L-ergothioneine (ET), is avidly accumulated in many tissues, especially the eye. However its relationship to AMD is unclear. Here, we examined ET’s distribution in human ocular tissues and measured serum and intraocular ET levels in patients with neovascular AMD.

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Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 3 May 2024 / Approved: 7 May 2024 / Online: 7 May 2024 (11:48:13 CEST) Leow, D.M.K.; Cheah, I.K.M.; Chen, L.; Ng, Y.K.; Yeo, C.J.J.; Halliwell, B.; Ong, W.Y. Ergothioneine Mediated Neuroprotection of Human iPSC derived-Dopaminergic Neurons.. Preprints 2024, 2024050382.