Bart C. Jongbloets

Abstract The insular cortex integrates interoceptive and exteroceptive information to mediate bodily homeostasis, emotion and learning. However, the cellular and circuit substrates governing insular functions are poorly understood compared to primary cortices. Here we quantify dendritic morphology together with projections, electrical properties and/or local inputs of 1,130 mouse insular pyramidal neurons. Neurons are mapped onto a quantitative Nissl-derived model of the insula.

Chui Kong1,2 Yangzhen Wang1,3 Guihua Xiao1,3,4* 1School of Information Science and Technology, Fudan University, Shanghai, China 2Department of Communication Science and Engineering, Fudan University, Shanghai, China 3Department of Automation, Tsinghua University, Beijing, China 4BNRist, Tsinghua University, Beijing, China Introduction: The visual cortex is a key region in the mouse brain, responsible for processing visual information.

Introduction Pavlovian fear conditioning is one of the most used behavioral paradigms, which serves as a model to study the basic cellular and circuit mechanisms underlying associated learning in neural networks. In this paradigm, an aversive stimulus (unconditioned stimulus, US) is presented together with a cue (conditioned stimulus, CS), resulting in a formed association between these signals wherein the animal learns that the cue (i.e., the CS) predicts the US.