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Basil Michael

As seen in: Nature, BioRxiv, Cell Reports Medicine
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Articles by Basil Michael

Author Correction: Multiomic analysis of familial adenomatous polyposis reveals molecular pathways associated with early tumorigenesis

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By Edward D. Esplin, Casey Hanson, Si Wu, Aaron M Horning, Nasim Bararpour, Stephanie A. Nevins, Lihua Jiang, Kévin Contrepois, Hayan Lee, Tuhin Guha, Zheng Hu, Meredith A. Mills, Hassan Chaib, Roxanne Chiu, Ruiqi Jian, Joanne Chan, Mathew Ellenberger, Winston R. Becker, Bahareh Bahmani, Aziz K. Khan, Basil Michael, Annika K Weimer, Jeanne Shen, Samuel M. Lancaster, Emma Monte, Thomas V. Karathanos, Uri Ladabaum, Teri A. Longacre, Anshul Kundaje, Christina Curtis, William J. Greenleaf, James Ford, Michael Snyder, Rozelle Laquindanum, D. Glen Esplin
| Nature Verified
Correction to: Nature Cancer https://doi.org/10.1038/s43018-024-00831-z, published online 30 October 2024. In the version of this article initially published, the surname of Nasim Bararpour was misspelled (Barapour) and is now amended in the HTML and PDF versions of the article.
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An encyclopedia of the cord blood metabolome reveals maternal-fetal interactions and disease risk

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By Samuel Christopher Lancaster, Samson Mataraso, Jonathan Reiss, Kévin Contrepois, Basil Michael, Ian Simms, Michelle Gibson, Max Clary, Lettie McGuire, Frank Wong, Ethan Canfield, Daniel Cotter, TAO WANG, Ramesh Nair, Prabhakar Krishnan, Jonathan Bernstein, David Stevenson, Tina Cowan, Ekanath Srihari Rangan, Nima Aghaeepour, Maya Kasowski, Karl G. Sylvester, Michael Snyder Verified, Casandra A. Trowbridge, Matthew Ellenberger, P. Venkat Rangan, Ylayaly Katherine Bianco
| Cell Reports Medicine Verified
ArticleOnline now102548Open access 1Department of Genetics, Stanford University School of Medicine, 240 Pasteur Drive, Palo Alto, CA 94304, USA 2Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA 3Department of Biomedical Data Science, Stanford University School of Medicine, 1265 Welch Road, Stanford, CA 94305, USA 4Department of Pediatrics, Stanford University School of Medicine, 725 Welch Road,...
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Individual variations in glycemic responses to carbohydrates and underlying metabolic physiology - Nature Medicine

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By Yue Wu, Ben W. Ehlert, Ahmed A. Metwally, Dalia Perelman, Andrew Brooks, Fahim Abbasi, Basil Michael, Ekrem Ayhan, Yingzhou Lu, Frank Wong, Georg Gutjahr, Ekanath Srihari Rangan, Tao Wang, Helge Ræder, Tracey McLaughlin, Lettie McGuire
| Nature Verified
Abstract Elevated postprandial glycemic responses (PPGRs) are associated with type 2 diabetes and cardiovascular disease. PPGRs to the same foods have been shown to vary between individuals, but systematic characterization of the underlying physiologic and molecular basis is lacking. We measured PPGRs using continuous glucose monitoring in 55 well-phenotyped participants challenged with seven different standard carbohydrate meals administered in replicate.
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Integrative multi-omics profiling in human decedents receiving pig heart xenografts - Nature Medicine

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By Brian D. Piening, Maedeh Mohebnasab, Bo Xia, Jeffrey S. Stern, Weimin Zhang, Jacqueline I. Kim, David Andrijevic, Karen Abou Khalil, Ian Jaffe, Darragh O’Brien, Han Chen, Andrew Chang, Xiangping Lin, Alawi Habara, Feng-Xia Liang, Adriana Heguy, Basil Michael, Minna Kaikkonen, Nader Moazami, Ramin S Herati, Adam D. Griesemer, Manolis Kellis, Michael Snyder, Jef Boeke, Alexa K. Dowdell, Suvi Linna-Kuosmanen
| Nature Verified
Abstract In a previous study, heart xenografts from 10-gene-edited pigs transplanted into two human decedents did not show evidence of acute-onset cellular- or antibody-mediated rejection.
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Oxidative Stress is a shared characteristic of ME/CFS and Long COVID

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By Vishnu Shankar, Julie Wilhelmy, Basil Michael, Layla Cervantes
| BioRxiv
Abstract More than 65 million individuals worldwide are estimated to have Long COVID (LC), a complex multisystemic condition, wherein patients of all ages report fatigue, post-exertional malaise, and other symptoms resembling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). With no current treatments or reliable diagnostic markers, there is an urgent need to define the molecular underpinnings of these conditions.
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An exercise-inducible metabolite that suppresses feeding and obesity - Nature

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By Kévin Contrepois, Joon T. Kim, Xuchao Lyu, Peter-James H. Zushin, Robert Jansen, Basil Michael, Andrew Yang, Christian S. Carl, Andreas Stahl, Bente Kiens, Erik Richter, Michael Snyder, Jonathan Long
| Nature Verified
Abstract Exercise confers protection against obesity, type 2 diabetes and other cardiometabolic diseases1,2,3,4,5. However, the molecular and cellular mechanisms that mediate the metabolic benefits of physical activity remain unclear6. Here we show that exercise stimulates the production of N-lactoyl-phenylalanine (Lac-Phe), a blood-borne signalling metabolite that suppresses feeding and obesity.
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