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Articles by Benjamin Combes
Comment financer vos actions de QVCT et prévention santé au travail ?
Le budget est souvent le premier frein invoqué quand il s'agit de déployer une démarche QVCT ou un programme de prévention santé. Pourtant, la majorité des entreprises passent à côté de financements auxquels elles ont déjà droit, non pas parce que ces dispositifs sont secrets, mais parce qu'ils sont dispersés entre plusieurs interlocuteurs. Nous avons recensé sept leviers mobilisables. Voici comment les identifier et les actionner.
Multimodal neuroimaging elucidates the posterior-to-anterior gradient of nigrostriatal degeneration in Parkinson’s disease
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Abstract Parkinson’s disease (PD) exhibits a characteristic posterior-to-anterior gradient of striatal dopamine loss, yet the underlying upstream mechanisms remain unclear. We combined in vivo ¹⁸F-FPCIT dopamine transporter (DaT) PET/MRI, quantitative susceptibility mapping, and diffusion MRI tractography in 48 PD patients and 10 healthy controls to test whether substantia nigra pars compacta (SNc) iron and microstructural disruption mediate posterior putaminal vulnerability.
By Huamei Lin, Ying Zhang, Yixin Zhao, Benjamin Combes, Martin T. Henrich, Fanni F. Geibl, Wolfgang Oertel, Kuangyu Shi, Axel Rominger, Ping Wu, Jingjie Ge, Jing L. Wang, Jiaying Lu, Zizhao Ju, qian Xu, Huiwei Zhang, Yunhao Yang, Zengping Lin, Yihui Guan, Fengtao Liu, Jian Wang, Jiehui Jiang, Ruiqing Ni, Chuantao Zuo, Yiman Wei
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Nature
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Atelier nutrition en entreprise : 5 formats à croquer !
Entre télétravail, réunions à rallonge et snacks industriels dans les distributeurs, garder le cap sur une alimentation saine au travail relève parfois du parcours du combattant… Heureusement, il existe un remède simple et efficace : l’atelier nutrition en entreprise.
Living in Disadvantaged Neighborhoods: Experiential Narratives of Residents Facing Daily, Economic, Environmental, and Social Challenges
1. Introduction The value we place on life and how we define what a good life is are topics that have preoccupied philosophical thought since ancient times. The concept of “well-being” is present in very diverse examples of contemporary literature, from philosophy to economy and psychology, as well as in the recent debates around ecological and climate upheavals. “Ensuring healthy lives and promoting well-being for all at all ages” is one of the United Nations sustainable development goals.
L’entreprise régénératrice : vrai tournant RSE ou énième greenwashing ?
Si votre organisation se tient un peu à la page, il est probable que sa feuille de route en matière de responsabilité sociétale des entreprises (RSE) inclue un objectif de régénération, à l’instar de Volkswagen et de sa stratégie regenerate+ ou du groupe de luxe français Kering, comprenant des maisons comme Gucci, Saint Laurent, Balenciaga… Au-delà des déclarations d’intention de ces deux entreprises et de bien d’autres, vous avez peut-être du mal à conceptualiser dans quelle mesure un SUV ou...
Visualizing alpha‐synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo
1 INTRODUCTION Alpha-synucleinopathies such as Parkinson's disease (PD), dementia with Lewy bodies, and multiple system atrophy are some of the most common neurodegenerative diseases [1]. Neuronal inclusions formed by β-sheet-rich fibrillar alpha-synuclein (αSyn), termed Lewy bodies, pale bodies, and Lewy neurites, are pathological hallmarks of PD.
Spinal cord perfusion impairments in the M83 mouse model of Parkinson's disease
Abstract Metabolism and bioenergetics in the central nervous system play important roles in the pathophysiology of Parkinson's disease (PD). Here, we employed a multimodal imaging approach to assess oxygenation changes in the spinal cord of a transgenic M83 murine model of PD in comparison to non-transgenic littermates at 9-12 months-of-age.
Visualizing alpha-synuclein and iron deposition in M83 mouse model of Parkinson's disease in vivo
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Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, 4-repeat/full-length tau and alpha-synuclein
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How AI can enable a Sustainable Future
The planet is facing a fight. Climate change, rapid biodiversity loss, resource depletion and food and water security are just a few of the serious issues negatively impacting the Earth’s natural systems. The need to better manage them to avert further damage intensifies daily. A new report by PwC UK and Microsoft, How AI can enable a sustainable future, provides the first step in a larger conversation that must be had to address these problems.
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