Bin Gu
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Articles by Bin Gu
Modular Integrated Nanofabric Enabling Crosstalk-Free Temperature-Force Sensing and on-Demand Personal Thermal Management
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm78754-sup-0001-SuppMat.docx13.3 MB Supporting File 1: adfm78754-sup-0001-SuppMat.docx. adfm78754-sup-0002-VideoS1.mp43.3 MB Supporting File 2: adfm78754-sup-0002-VideoS1.mp4.
UniMoMo: Expert Merging-Based MoE Acceleration for Large Recommendation Models
Published on Aug 9 ยท Submitted by Changjiang Jiang on Aug 12 Abstract UniMoMo compresses trained recommendation mixture-of-experts models into smaller standard MoE checkpoints via functional similarity grouping and layer-adaptive protection, preserving accuracy while accelerating inference. Sparse mixture-of-experts (MoE) layers expand recommendation capacity through conditional computation, yet a trained checkpoint still stores and routes over its full expert bank.
A Biomimetic Dual-Targeting Nano-APA-Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy
1 Introduction Head and neck squamous cell carcinoma (HNSC) remains a formidable global health challenge, with oral squamous cell carcinoma (OSCC) representing its most prevalent and insidious subtype [1, 2]. Despite multimodal therapeutic strategies encompassing surgery, radiotherapy, and systemic chemotherapy, the 5-year overall survival rate for HNSC patients has stagnated, largely due to high rates of locoregional recurrence, distant metastasis, and profound therapeutic resistance [3, 4].
Cannabidiol corrects sleep deficits and reduces spontaneous seizures in Angelman syndrome model mice
Abstract The off-label use of cannabidiol (CBD) has outpaced investigation. We assessed the effects of CBD in Angelman syndrome model mice lacking the Ube3a gene and found that chronic injection of CBD increased rapid-eye movement sleep during the dark cycle, restored “Siesta”, improved sleep homeostasis, and reduced spontaneous seizures following flurothyl kindling.
High-performance RT-DETR model for industrial defect detection with semantic guidance and hierarchical attention
Citation: Huang J, Gu B, Tang Y, Xu B, Li P, Ye J, et al. (2026) High-performance RT-DETR model for industrial defect detection with semantic guidance and hierarchical attention. PLoS One 21(5): e0348807. https://doi.org/10.1371/journal.pone.0348807 Editor: Ning Cai, Beijing University of Posts and Telecommunications, CHINA Received: October 19, 2025; Accepted: April 21, 2026; Published: May 12, 2026 Copyright: © 2026 Huang et al.
UBE3A isoform-selective and non-selective contributions to Angelman syndrome phenotypes - Molecular Psychiatry
Abstract Angelman syndrome (AS) is a neurodevelopmental disorder caused by UBE3A loss. In humans, UBE3A generates three isoforms that localize to distinct subcellular compartments—one mainly nuclear and two cytoplasmic. The nuclear and most highly expressed cytoplasmic UBE3A isoform are highly conserved in mice, whereas the cytoplasmic human isoform accounting for just ~1% of total UBE3A has no mouse counterpart.
Case Report: Sellar collision tumor consisting of pituitary adenoma and craniopharyngioma, with literature review
Abstract Collision tumors harbor two distinct histological features at the same site, and sellar collision tumors of pituitary adenoma (PA) and craniopharyngioma (CP) are extremely rare. This report presents a 64-year-old female with fatigue, anorexia, palpitations, dizziness, and exertional dyspnea. Examinations confirmed pan-hypopituitarism and life-threatening electrolyte disturbances. Preoperative MRI showed a homogeneous lesion indistinguishable from a standard macroadenoma.
SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mouse
Abstract NUT carcinoma (NC) is a highly aggressive malignancy driven by BRD4::NUTM1 and other NUTM1 fusion oncogenes. BRD4::NUTM1 aberrantly activates transcription factors (TFs) linked to basal progenitor identity, producing poorly differentiated squamous phenotypes. Among these TFs, SOX2 has been proposed as a critical oncogenic driver, but its functional requirement in NC has not been tested in vivo.
Fabrication and Electrochemical Performance of Br-Doped Na3PS4 Solid-State Electrolyte for Sodium-Sulfur Batteries via Melt-Quenching and Hot-Pressing
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Ultra-high elongation MXene/polyurethane porous fibers with passive insulation, passive radiative heating and active heating properties for personal thermal management
Cold weather can harm human health and even threaten human life.
A Novel Method for Increasing Phase‐Change Microcapsules in Nanofiber Textile through Electrospinning
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202412089-sup-0001-SuppMat.docx2.4 MB Supporting Information References 1a) , , , , , , , , , , , Nat. Rev. Cardiol. 2021, 18, 581; b) , , Science 2023, 382, 644; c) , , , , , , Energy Environ. Sci. 2024, 17, 4498. 2, , , , , , , , , , , , , , , , , , , , , , , , , , , , Science 2021, 373, 692. 3a) , , , , , , , , , Joule 2019, 3, 1478; b) , , , , , ACS Nano 2023, 17, 18308.
Texture of Hot-Compressed Metastable β-Titanium Alloy Ti5321 Studied by Neutron Diffraction
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Advances in Immunomodulatory Mesoporous Silica Nanoparticles for Inflammatory and Cancer Therapies
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A fibronectin gradient remodels mixed-phase mesoderm
Abstract Physical processes ultimately shape tissue during development. Two emerging proposals are that cells migrate toward stiffer tissue (durotaxis) and that the extent of cell rearrangements reflects tissue phase, but it is unclear whether and how these concepts are related. Here, we identify fibronectin-dependent tissue stiffness as a control variable that underlies and unifies these phenomena in vivo.
Target Reprogramming the 3′UTR of Tumor‐Suppressor Genes by a siRNA Composite Nanoparticle for Glioblastoma Therapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202400837-sup-0001-SuppMat.docx3.1 MB Supporting Information References 1, , , , , , , , , , , J. Hematol. Oncol. 2016, 9, 77. 2, , J. Neuropathol. Exp. Neurol. 2005, 64, 479. 3, , , , , , , , Front. Genet. 2019, 10, 419. 4, , , , , , , , , , Oncol. Lett. 2020, 20, 332. 5, , , , , , , , , , , , , , , Science 2014, 344, 1396. 6, , , Expert Rev. Mol. Diagn. 2012, 12, 383.
Chinese Multilateralism in the Asian Infrastructure Investment Bank (AIIB)
This book reflects the latest legal development of the Asian Infrastructure Investment Bank (AIIB), and makes direct and positive responses—it uses first-hand, authoritative information and makes insightful and persuasive analyses in addressing those concerns.
Rapid discrimination of four Salmonella enterica serovars: A performance comparison between benchtop and handheld Raman spectrometers
1 INTRODUCTION Salmonella enterica is a Gram-negative pathogenetic bacterium of the Enterobacteriaceae family with more than 2600 serotypes.1, 2 Improper cooking, reheating and handling of food can lead to Salmonella outbreaks, and the presence of Salmonella in any ready-to-eat food should be inhibited.
Energy Characteristics in the Flow Channel of the Shaft-Type Tubular Pumping Station Considering Tides
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
The Political Calculus Behind Xi Jinping’s Emphasis on Climate Leadership - The Diplomat
On February 1, 2024, after renewing diplomatic ties with Nauru, a former ally of Taiwan, Qian Bo, China’s particular envoy to Pacific Island nations, expressed China’s willingness to cooperate with Nauru in combating local weather change. This initiative is a part of a wider development in China’s engagement with creating nations on environmental points. Over the previous decade, China has undergone a major shift in its stance on local weather change.
The Political Calculus Behind Xi Jinping’s Emphasis on Climate Leadership
On February 1, 2024, after renewing diplomatic ties with Nauru, a former ally of Taiwan, Qian Bo, China’s special envoy to Pacific Island nations, expressed China’s willingness to cooperate with Nauru in combating climate change. This initiative is part of a wider trend in China’s engagement with developing countries on environmental issues. Over the past decade, China has undergone a significant shift in its stance on climate change.
2023 5th International Conference on Software Engineering and Development (ICSED)
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“Direct Visualization and 3D Reconstruction of Conductive Filaments in SiO2 Material-Based Memristive Device
“Direct Visualization and 3D Reconstruction of Conductive Filaments in SiO2 Material-Based Memristive Device Observation of conductive filaments has greatly aided the development of theoretical models of memristive devices. In this work, we visualized and reconstructed the conductive filaments in a Cu/Cu-doped SiO2/W device employing a focused ion beam (FIB) as a milling technique.
Research on the Transient Characteristics of a Three-Stream Adaptive Cycle Engine
1. Introduction An adaptive cycle engine is one of the ideal engines for future multi-mission combat aircraft [1]. It has two working modes: the thrust priority mode and the specific fuel consumption (SFC) priority mode. It can switch between the two modes through the adjustment of geometric mechanisms provided that the same engine has both high specific thrust characteristics in a high-power state and low fuel consumption characteristics in a low-power state.
[2309.05906] Correct-by-Construction for Hybrid Systems by Synthesizing Reset Controller
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Synergistic Effect Enhancing Baeyer‐Villiger Oxidation Performance of Resin‐Derived‐Carbon Supported FeCe Bimetallic Catalyst
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Simultaneous Passive Cooling and Humidity Control via the Fiber-Encapsulated Gel Structure
Radiative cooling is a promising technology that offers benefits such as reducing cooling energy demand, mitigating climate change impacts, and contributing to sustainable development. However, previous radiative cooling technologies are unable to manage humidity, which is crucial and energy-intensive in many applications. Therefore, it is necessary to extend the capabilities of radiative coolers to include humidity control.
Nonlinear electronic stopping of negatively charged particles in liquid water
Abstract We present real-time time-dependent density-functional-theory calculations of the electronic stopping power for negative and positive projectiles (electrons, protons, antiprotons, and muons) moving through liquid water. After correction for finite mass effects, the nonlinear stopping power obtained in this paper is significantly different from the previously known results from semiempirical calculations based on the dielectric response formalism.
Midface Prelamination by using a Three-dimensional Cervicothoracic Prefabricated Flap
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Durotaxis bridges phase transition as a function of tissue stiffness in vivo
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Behavioral features and disorganization of oscillatory activity in C57BL/6J mice after acute low dose MK-801 administration
Introduction Schizophrenia is one of the top 20 leading causes of disability (2018) that affects approximately 0.7% worldwide (McGrath et al., 2008; Moreno-Küstner et al., 2018). Economic burdens related to schizophrenia are as high as more than $150 billion annually in the United States (Cloutier et al., 2016; Jin and Mosweu, 2017).
Chinese Herbal Medicine for Treating Epilepsy
Introduction Epilepsy is a common and chronic neurological disease. The etiologies of epilepsy are defined as structural, genetic, infectious, metabolic, immune, and unknown, which are proposed from International League Against Epilepsy classification system in 2017 (Scheffer et al., 2017).
A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients
Loading metrics Open Access Peer-reviewed Research Article Yuxin Chen , Xin Tong , Yang Li, Bin Gu, Jiawei Yan, Yong Liu, Han Shen, Rui Huang , Chao Wu Yuxin Chen, Xin Tong, Yang Li, Bin Gu, Jiawei Yan, Yong Liu, Han Shen, Rui Huang, Chao Wu Published: September 10, 2020 https://doi.org/10.1371/journal.ppat.1008796 Figures Abstract There is an urgent need for effective treatment and preventive vaccine to contain this devastating global pandemic, which requires a comprehensive understanding of...
MiR-27b-3p suppresses glioma development via targeting YAP1
Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing, Jiangsu 210009, P.R. China. Received August 20, 2019. Accepted November 29, 2019. Ambros V. 2004. The functions of animal microRNAs. Nature 431(7006): 350-355 Crossref, Medline, ISI, Google Scholar. Bartel DP. 2009. MicroRNAs: target recognition and regulatory functions. Cell 136(2): 215-233 Crossref, Medline, ISI, Google Scholar. Chen D, Si W, Shen J, Du C, Lou W, Bao C, et al. 2018.
linking academia, business and industry through research
Home Full-text access for editors The effects of varying levels of mental workload on motor imagery based brain-computer interface by Bin Gu; Long Chen; Yufeng Ke; Yijie Zhou; Haiqing Yu; Kun Wang; Dong Ming International Journal of Embedded Systems (IJES), Vol.
Cannabidiol attenuates seizures and EEG abnormalities in Angelman syndrome model mice
As with individuals with AS, mice with maternal loss of Ube3a exhibit epileptic phenotypes. For example, AS mice on a 129 background have elevated seizure responses to acoustic stimuli (9, 10, 14). We verified that AS model mice (on a 129 background) had more frequent audiogenic tonic convulsions than did WT littermates (Figure 1). We found that acute treatment with CBD at 100 mg/kg significantly reduced the frequency and severity of seizures triggered by acoustic stimuli (Figure 1).
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